Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 237
interventional 190
Observational 46
Registry 1

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 63
Drug|placebo 34
Device 31
Procedure 20
Drug|Other 6
Other 6
Drug|Procedure 5
Device|Procedure 4
Device|Other 3
Biological|placebo 2
Dietary Supplement|placebo 2
Behavioral 1
Behavioral|Drug 1
Biological 1
Biological|Device 1
Combination Product 1
Combination Product|Other 1
Device|Drug 1
Device|Drug|Procedure 1
Diagnostic Test 1
Diagnostic Test|Other 1
Drug|Other|placebo 1
Drug|Radiation 1
Other|placebo 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 91
Canada 23
NA 16
Germany 6
France 5
Thailand 4
China 3
Finland 3
Japan 3
Belgium 2
Czechia 2
Israel 2
Italy 2
Norway 2
Turkey 2
Australia|New Zealand 1
Belgium|Germany 1
Belgium|Israel 1
Bulgaria|Canada|Czechia|Estonia|Germany|Netherlands|Norway|Poland|Russian Federation|Spain|Sweden|Ukraine 1
Denmark 1
Finland|Netherlands 1
Germany|Poland 1
Italy|United States|Canada|Greece|Hungary|Lithuania|Poland|Romania|Spain 1
Korea, Republic of 1
Poland 1
Poland|Australia|Austria|Czechia|New Zealand 1
Sweden 1
Switzerland 1
United States|Argentina 1
United States|Argentina|Chile|Costa Rica|Czech Republic|Estonia|Germany|India|Lithuania|Mexico|Poland|Russian Federation|Slovakia| 1
United States|Australia|Czechia|New Zealand|Poland|Spain|United Kingdom 1
United States|Belgium|Canada|Czechia|France|Germany|Hungary|Mexico|Poland|Portugal|Russian Federation|Spain|Ukraine|United Kingdom 1
United States|Belgium|Spain|Sweden 1
United States|Canada 1
United States|Canada|Czechia|Germany|Mexico|Poland|Portugal|Russian Federation|Ukraine|United Kingdom 1
United States|Canada|United Kingdom 1
United States|Czechia|Ukraine 1
United States|Poland 1
United States|United Kingdom 1

Sites per Study

Site_count Study_Count
1 124
2 13
3 6
4 7
5 4
6 4
7 1
9 2
10 1
11 2
13 1
14 1
18 2
19 2
20 2
22 1
25 1
28 1
33 1
35 2
37 1
40 1
42 1
43 1
45 1
51 1
53 1
54 1
68 1
79 1
87 1
89 1

Phase

Phase Study_Count
N/A 79
Phase 3 36
Phase 4 34
Phase 2 20
Phase 1/Phase 2 7
Phase 1 6
Early Phase 1 5
Phase 2/Phase 3 3

Number of Arms

Number_of_Arms Count_of_Studies
1 39
2 109
3 18
4 7
5 1
13 1
NA 15

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 9 8.00000 6.00000 14.00000 5.00 40.00000 5.0000 14.0000
1st Qu. 20 30.00000 24.00000 21.00000 32.75 45.00000 59.7500 48.2500
Median 22 60.00000 38.50000 30.00000 60.00 50.00000 195.0000 83.0000
Mean 76 97.68831 40.83333 34.85714 140.15 63.33333 286.4444 149.7647
3rd Qu. 29 98.00000 44.00000 40.00000 100.00 75.00000 408.5000 189.0000
Max. 300 1000.00000 97.00000 78.00000 981.00 100.00000 981.0000 762.0000

Trial Group Type

group_type Group_Count
Experimental 162
Active Comparator 104
Placebo Comparator 58
Other 15
NA 15
No Intervention 12
Sham Comparator 6

Intervention Model

intervention_model Study_Count
Parallel Assignment 134
Single Group Assignment 48
Crossover Assignment 5
Factorial Assignment 1
Sequential Assignment 1
NA 1

Primary Purpose

primary_purpose Study_Count
Treatment 152
Diagnostic 10
Prevention 7
Supportive Care 6
Other 5
NA 4
Basic Science 3
Device Feasibility 1
Educational/Counseling/Training 1
Health Services Research 1

Observational Studies

Studies by Country

Country Study_Count
United States 24
NA 7
Germany 4
Thailand 2
United Kingdom 2
Austria|Bahrain|China|Egypt|France|Germany|Indonesia|Jordan|Kuwait|Lebanon|Malaysia|Netherlands|Pakistan|Philippines|Romania|Saudi Arabia|Singapore|United Arab Emirates|Yemen 1
Canada 1
Czechia 1
France 1
Korea, Republic of 1
Spain 1
United States|Australia 1

Sites per Study

Site_count Study_Count
1 37
2 3
3 2
6 1
16 1
19 1
20 1

Enrollment Metrics

Measure Observational
Min 12.000
1st Qu 33.000
Median 99.000
Mean 9619.689
3rd Qu 300.000
Max 239306.000

Observation Model

observational_model Study_Count
Cohort 24
Case-Only 9
Case-Control 3
Case Control 3
Other 3
NA 2
Ecologic or Community 1
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 36
Cross-Sectional 4
Retrospective 4
NA 2

Registries

Studies by Country

Country Study_Count
NA 1

Sites per Study

Site_count Study_Count
1 1

Enrollment Metrics

Measure Registries
Min 71
1st Qu 71
Median 71
Mean 71
3rd Qu 71
Max 71

Registry Model

observational_model Study_Count
Cohort 1

Time Perspective

time_perspective Study_Count
Prospective 1

Follow-up

target_duration Study_Count
3 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03390257 Study to Evaluate the Safety and Initial Effectiveness of the Sinuswayâ„¢ for Endoscopy of Sinuses in Conjunction With BSD https://ClinicalTrials.gov/show/NCT03390257 Completed 3NT Medical Ltd. 2018-03-21
NCT03369717 Use of Perioperative Antibiotics in Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT03369717 Recruiting Montefiore Medical Center 2022-01-31
NCT03822962 Pain Management Following Sinus Surgery https://ClinicalTrials.gov/show/NCT03822962 Recruiting University of Nebraska 2020-12-31
NCT03336671 Management of Pediatric Chronic Rhinosinusitis in Asthmatic Children https://ClinicalTrials.gov/show/NCT03336671 Recruiting State University of New York - Upstate Medical University 2020-07-01
NCT03304951 Sinopsys® Lacrimal Stent Indicated for Sinus Irrigation https://ClinicalTrials.gov/show/NCT03304951 Completed Sinopsys Surgical 2016-08-31
NCT03280550 A Clinical Trial of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps https://ClinicalTrials.gov/show/NCT03280550 Completed Hoffmann-La Roche 2019-03-11
NCT03188822 Steroid Delivery to the Frontal Sinus Opening With a Bioabsorbable Implant vs. a Bioabsorbable Nasal Dressing https://ClinicalTrials.gov/show/NCT03188822 Recruiting University of Rochester 2020-12-31
NCT03122795 Sinonasal Microbiome Transplant as a Therapy for Chronic Rhinosinusitis Without Nasal Polyps (CRSsNP) https://ClinicalTrials.gov/show/NCT03122795 Completed Region Skane 2018-12-17
NCT03086070 Omeprazole 20 mg in Patients With Laryngopharyngeal reflux and Comorbid Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT03086070 Completed Children’s Hospital Srebrnjak 2010-04-30
NCT03068728 Analysis of Hemostatic Agents Compared to Physiologic Hemostasis https://ClinicalTrials.gov/show/NCT03068728 Completed St. Louis University 2017-04-10
NCT02975310 In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps https://ClinicalTrials.gov/show/NCT02975310 Recruiting Ottawa Hospital Research Institute 2021-06-30
NCT02972281 Systematic Search for Primary Immunodeficiency in Adults With Infections https://ClinicalTrials.gov/show/NCT02972281 Recruiting University Hospital, Lille 2020-03-31
NCT02967731 480 Biomedical Sinus Drug Depot https://ClinicalTrials.gov/show/NCT02967731 Completed 480 Biomedical 2017-12-19
NCT02927834 Oral Steroids in Chronic Rhinosinusitis Without Nasal Polyps https://ClinicalTrials.gov/show/NCT02927834 Completed Loma Linda University 2018-12-31
NCT02924103 Contamination Free Bacterial Swap https://ClinicalTrials.gov/show/NCT02924103 Completed Rigshospitalet, Denmark 2018-03-01
NCT02880514 In-office Placement of the Propel Mini Sinus Implant in the Frontal Sinus Ostia https://ClinicalTrials.gov/show/NCT02880514 Completed Intersect ENT 2016-12-31
NCT02874144 Anti-Inflammatory Agent in Sinusitis https://ClinicalTrials.gov/show/NCT02874144 Enrolling by invitation Northwestern University 2020-03-31
NCT02855931 Study to Compare Resection Versus Preservation of the Middle Turbinate in Surgery for Nasal Polyps https://ClinicalTrials.gov/show/NCT02855931 Completed Université de Sherbrooke 2017-12-31
NCT02077322 Rates of Middle Meatal Synechia Formation Following Functional Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT02077322 Completed St. Paul’s Hospital, Canada 2017-05-31
NCT02772419 Study of Benralizumab (KHK4563) in Patients With Eosinophilic Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT02772419 Completed Kyowa Kirin Co., Ltd. 2017-03-27
NCT02748070 Perioperative Oral Steroids for Chronic Rhinosinusitis Without Polyps (CRSsNP) https://ClinicalTrials.gov/show/NCT02748070 Completed Stanford University 2019-07-31
NCT02746042 Sinupret Extract Coated Tablets in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT02746042 Completed Bionorica SE 2017-07-26
NCT02743871 Study Of PF-06817024 In Healthy Subjects, In Patients With Chronic Rhinosinusitis With Nasal Polyps And in Patients With Atopic Dermatitis https://ClinicalTrials.gov/show/NCT02743871 Active, not recruiting Pfizer 2021-02-14
NCT02696850 The Impact Of The Addition Of Budesonide To Low-Pressure, High-Volume Saline Sinus Irrigation For Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT02696850 Completed Washington University School of Medicine 2017-04-13
NCT02687438 The PIO (Propel In Office) III Study of In-office Placement of a Steroid-Eluting Implant Immediately Following Ethmoid Sinus Surgery https://ClinicalTrials.gov/show/NCT02687438 Completed ENT and Allergy Associates, LLP 2016-02-29
NCT02668302 The PIO II Study: In-office Post-op Placement of a Steroid-eluting Sinus Implant https://ClinicalTrials.gov/show/NCT02668302 Completed Collin County Ear Nose & Throat 2016-11-30
NCT02582099 The Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis and Recurrent Sinusitis https://ClinicalTrials.gov/show/NCT02582099 Recruiting Mahidol University 2019-06-30
NCT02562924 The Efficacy of MEDIHONEY® for Chronic Rhinosinusitis With Nasal Polyposis After Functional Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT02562924 Completed University of Vermont Medical Center 2017-12-31
NCT02533206 Pilot Study of The EPIC Trial https://ClinicalTrials.gov/show/NCT02533206 Active, not recruiting Ottawa Hospital Research Institute 2021-06-30
NCT02502084 Safety and Effectiveness Evaluation of the Sinusway Device for Endoscopy of the Nasal Cavity and Paranasal Sinuses https://ClinicalTrials.gov/show/NCT02502084 Completed 3NT Medical Ltd. 2017-04-30
NCT02463279 SinuSys Patency of Frontal Recess and Sphenoid Sinus Ostia Study https://ClinicalTrials.gov/show/NCT02463279 Completed SinuSys Corporation 2015-10-31
NCT02403479 The Effectiveness of Topical Silver Colloid in Treating Patients With Recalcitrant Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT02403479 Completed Lawson Health Research Institute 2016-03-06
NCT02340000 Clinical Trial of the Treatment of Acute Sinusitis With Standard-dose Versus High-dose Amoxicillin/Clavulanate https://ClinicalTrials.gov/show/NCT02340000 Completed Albany Medical College 2017-02-27
NCT02307825 Azithromycin for Patients With Chronic Rhinosinusitis Failing Medical and Surgical Therapy https://ClinicalTrials.gov/show/NCT02307825 Completed Centre hospitalier de l’Université de Montréal (CHUM) 2017-08-15
NCT02297243 Sinopsys Lacrimal Stent Indicated for Sinus Irrigation https://ClinicalTrials.gov/show/NCT02297243 Completed Sinopsys Surgical 2016-02-29
NCT02296814 Efficacy and Safety of Sinusitis Hevert SL Tablets Compared to Placebo in Adult Patients With Acute, Uncomplicated Rhinosinusitis https://ClinicalTrials.gov/show/NCT02296814 Completed Hevert-Arzneimittel GmbH & Co. KG 2015-04-30
NCT02291549 S8 Sinus Implant in Chronic Sinusitis Patients With Recurrent Nasal Polyps https://ClinicalTrials.gov/show/NCT02291549 Completed Intersect ENT 2016-10-31
NCT02228720 Clinical Evaluation of Propel Nova Sinus Implant in Peripheral Sinus Ostia https://ClinicalTrials.gov/show/NCT02228720 Completed Intersect ENT 2014-10-31
NCT02194062 Comparison of Nasal Steroids After FESS in CRSwNP https://ClinicalTrials.gov/show/NCT02194062 Completed Yale University 2015-07-31
NCT02191046 Effect of Squeezable Bottle Nasal Irrigation Device in Children With Sinusitis https://ClinicalTrials.gov/show/NCT02191046 Completed Thammasat University 2014-05-31
NCT02182492 Efficacy of Macrolide and Glucocorticoid in the Treatment of Chronic Rhinosinusitis After Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT02182492 Completed Huazhong University of Science and Technology 2015-12-31
NCT02170337 A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AMG 282 in Healthy Subjects and Subjects With Chronic Rhinosinusitis With Nasal Polyps https://ClinicalTrials.gov/show/NCT02170337 Completed Amgen 2016-05-31
NCT02079792 The Optimal Head Position for Distributing Topical Nasal Medication Using the Mucosal Atomization Device https://ClinicalTrials.gov/show/NCT02079792 Completed St. Paul’s Hospital, Canada 2015-06-30
NCT03358329 Safety Evaluation of Repeat Placement of the S8 Sinus Implant in Chronic Sinusitis Patients With Nasal Polyps (ENCORE) https://ClinicalTrials.gov/show/NCT03358329 Completed Intersect ENT 2019-01-17
NCT01990820 Study for the Management of Pediatric Chronic Rhinosinusitis With or Without Balloon Sinuplasty https://ClinicalTrials.gov/show/NCT01990820 Completed NorthShore University HealthSystem 2016-09-29
NCT01988779 Oral Versus Topical Antibiotics for Chronic Rhinosinusitis Exacerbations https://ClinicalTrials.gov/show/NCT01988779 Active, not recruiting University of Rochester 2017-09-11
NCT04420052 Effects of Osteopathic Manipulative Treatment in Chronic Non-allergic Rhinosinusitis https://ClinicalTrials.gov/show/NCT04420052 Recruiting Institut des Hautes Etudes Osteopathiques de Nantes 2021-06-01
NCT01934231 Study to Assess the Efficacy and Safety of Potassium Clavulanate/Amoxicillin in Children With Acute Bacterial Rhinosinusitis https://ClinicalTrials.gov/show/NCT01934231 Completed GlaxoSmithKline 2013-11-07
NCT01919411 Prophylactic Antibiotics After Functional Endoscopic Sinus Surgery: a Randomized, Double-blind Placebo Controlled Trial https://ClinicalTrials.gov/show/NCT01919411 Completed Massachusetts Eye and Ear Infirmary 2018-09-30
NCT01907204 Evaluation of Inhaled Treatment in Sinusitis https://ClinicalTrials.gov/show/NCT01907204 Completed Cliniques universitaires Saint-Luc- Université Catholique de Louvain 2013-08-31
NCT01894503 Safety and Performance of the Steroid-Releasing S8 Sinus Implant https://ClinicalTrials.gov/show/NCT01894503 Completed Intersect ENT 2013-10-31
NCT01825408 Duration of Antibiotic Therapy as Part of Maximal Medical Therapy for Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT01825408 Completed University of North Carolina, Chapel Hill 2014-06-30
NCT01806103 Antimicrobial Stewardship for Primary Care Pediatricians https://ClinicalTrials.gov/show/NCT01806103 Completed Children’s Hospital of Philadelphia 2011-06-30
NCT01732536 Steroid-Releasing S8 Sinus Implant for Recurrent Nasal Polyps https://ClinicalTrials.gov/show/NCT01732536 Completed Intersect ENT 2013-11-30
NCT01717274 Hot Saline Irrigation Study https://ClinicalTrials.gov/show/NCT01717274 Completed St. Paul’s Hospital, Canada 2015-03-31
NCT01714687 Comparison of Balloon Sinuplasty In-Office Versus Medical Management for Recurrent Acute Sinusitis Patients (CABERNET) https://ClinicalTrials.gov/show/NCT01714687 Completed Acclarent 2015-10-01
NCT01706952 Comparison of Topical Vasoconstriction in Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT01706952 Completed McGill University Health Centre/Research Institute of the McGill University Health Centre 2013-12-31
NCT01706484 Efficacy and Safety of Two Dosages of a Herbal Medicinal Product (Dry Extract BNO 1016) in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT01706484 Completed Bionorica SE 2014-04-30
NCT01700725 Gulf War Illness Nasal Irrigation Study https://ClinicalTrials.gov/show/NCT01700725 Completed University of Wisconsin, Madison 2016-06-30
NCT01691677 beCLomethasone Efficacy in Acute Rhinosinusitis - CLEAR Study https://ClinicalTrials.gov/show/NCT01691677 Completed Chiesi Farmaceutici S.p.A. 2014-01-31
NCT04085536 Prospective Study on the Efficacy of Exclusive Odontological and Medical Treatment in Chronic Dental Maxillary Sinusitis https://ClinicalTrials.gov/show/NCT04085536 Recruiting Centre Hospitalier Intercommunal Creteil 2021-10-15
NCT01623323 Study Evaluating the Safety of Intranasal Administration of 400 μg of Fluticasone Propionate Twice a Day (BID) Using a Novel Bi-Directional Device in Subjects With Chronic Sinusitis With or Without Nasal Polyps https://ClinicalTrials.gov/show/NCT01623323 Completed Optinose US Inc. 2015-03-31
NCT01623050 Safety and Performance of the SinuSys Dilation System for Dilation of the Maxillary Sinus Ostium https://ClinicalTrials.gov/show/NCT01623050 Completed SinuSys Corporation 2013-06-30
NCT01612780 Trans-Nasal Maxillary Multi-Sinus Balloon Dilation Study https://ClinicalTrials.gov/show/NCT01612780 Completed Entellus Medical, Inc. 2013-10-31
NCT01608308 Intraoperative and Post-operative Analgesic Effect of IV Acetaminophen for Sinus Surgery https://ClinicalTrials.gov/show/NCT01608308 Completed The University of Texas Health Science Center, Houston 2014-09-30
NCT01575223 Saline Irrigation After Surgery in Patients With Chronic Sinusitis https://ClinicalTrials.gov/show/NCT01575223 Completed Samuel Lunenfeld Research Institute, Mount Sinai Hospital 2014-04-30
NCT01569048 Randomized Controlled Trial to Evaluate of Dexmedetomidine for the Effect on Operative Visibility in Patients Undergoing Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT01569048 Completed Yonsei University 2014-02-28
NCT01564355 Postoperative Systemic Corticosteroids When Utilizing a Steroid-Eluting Spacer Following Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT01564355 Completed University of Calgary 2013-09-30
NCT01525862 XprESS Maxillary Balloon Dilation Study https://ClinicalTrials.gov/show/NCT01525862 Completed Entellus Medical, Inc. 2013-01-31
NCT01525849 Randomized Evaluation of Maxillary Antrostomy Versus Ostial Dilation Efficacy Through Long-Term Follow-Up https://ClinicalTrials.gov/show/NCT01525849 Completed Entellus Medical, Inc. 2014-02-28
NCT01442740 15-Degree Tilt, Head Up, Feet Down Body Position for Sinus Surgery Patients https://ClinicalTrials.gov/show/NCT01442740 Completed St. Paul’s Hospital, Canada 2012-03-31
NCT01420471 Medicated Punctured-Glove-Finger Spacer Study https://ClinicalTrials.gov/show/NCT01420471 Completed St. Paul’s Hospital, Canada 2012-05-31
NCT01405339 Budesonide Application Via Mucosal Atomization Device as a Treatment for Chronic Rhinosinusitis When Utilized as a Topical Nasal Steroid Spray https://ClinicalTrials.gov/show/NCT01405339 Completed St. Paul’s Hospital, Canada 2013-05-31
NCT01350193 Manuka Honey Irrigation After Sinus Surgery https://ClinicalTrials.gov/show/NCT01350193 Completed St. Paul’s Hospital, Canada 2013-01-31
NCT04291118 Assessing Improvement in Cognitive Deficit in CRS in Patients Treated With Medical Vs Surgical Management https://ClinicalTrials.gov/show/NCT04291118 Recruiting St. Paul’s Hospital, Canada 2021-09-01
NCT04286542 Mediators in Nasal Hyperreactivity in Allergic Rhinitis and Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT04286542 Recruiting Universitaire Ziekenhuizen Leuven 2021-12-31
NCT04241016 Endoscopic Sinus Surgery in Recurrent Acute Rhinosinusitis https://ClinicalTrials.gov/show/NCT04241016 Recruiting Oulu University Hospital 2024-12-31
NCT04171167 The Causal Relation of Nasal Nitric Oxide Levels to the Severity of Chronic Rhinosinusitis and Its Inflammatory Phenotype https://ClinicalTrials.gov/show/NCT04171167 Recruiting Tampere University Hospital 2020-12-31
NCT04163978 Nitric Oxide Releasing Sinus Irrigation (NOSi) to Treat Recalcitrant Chronic Rhinosinusitis (RCRS) https://ClinicalTrials.gov/show/NCT04163978 Recruiting Sanotize Research and Development corp. 2020-04-30
NCT04104594 Olfaction and Inflammation in Chronic Rhinosinusitis With Nasal Polyps https://ClinicalTrials.gov/show/NCT04104594 Recruiting Centre Hospitalier Universitaire de Saint Etienne 2020-10-31
NCT04097613 Betadine Rinses for Chronic Rhinosinusitis Prospective Cohort Study https://ClinicalTrials.gov/show/NCT04097613 Completed St. Paul’s Hospital, Canada 2019-04-01
NCT04093193 Debridement and Functional Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT04093193 Recruiting St. Paul’s Hospital, Canada 2021-07-01
NCT04048174 Safety and Efficacy of Lactococcus Lactis Probiotic Bacteria for the Treatment of Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT04048174 Completed Centre hospitalier de l’Université de Montréal (CHUM) 2015-12-02
NCT04048070 The Effect of Enhanced Recovery After Surgery in Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT04048070 Completed Beijing Tongren Hospital 2018-10-15
NCT04041609 LYR-210 Depot (LYR-210) for Adult Subjects With Chronic Sinusitis (LANTERN Study) https://ClinicalTrials.gov/show/NCT04041609 Active, not recruiting Lyra Therapeutics 2020-09-30
NCT03229551 Xylitol for Chronic Sinusitis https://ClinicalTrials.gov/show/NCT03229551 Recruiting Ochsner Health System 2020-02-29
NCT03979209 Potential for Cortisol Suppression With the Use of High Volume Nasal Mometasone Irrigations in Varying Dosages. https://ClinicalTrials.gov/show/NCT03979209 Recruiting Rush University Medical Center 2019-08-23
NCT03970655 Functional Endoscopic Sinus Surgery Study https://ClinicalTrials.gov/show/NCT03970655 Recruiting University of Florida 2021-07-31
NCT03960580 Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Sinusitis Without the Presence of Nasal Polyps https://ClinicalTrials.gov/show/NCT03960580 Recruiting Optinose US Inc. 2021-04-30
NCT03956862 GB001 in Adult Subjects With Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT03956862 Active, not recruiting Gossamer Bio Inc. 2020-07-31
NCT03943121 The Effects of Steroid-eluting Stent Implant for the Treatment of Eosinophilic Chronic Rhinosinusitis With Nasal Polyps https://ClinicalTrials.gov/show/NCT03943121 Recruiting Beijing Tongren Hospital 2019-09-01
NCT03878355 A Study of Different Endoscopic Surgery Procedures in Eosinophilic Chronic Rhinosinusitis With Nasal Polyps https://ClinicalTrials.gov/show/NCT03878355 Completed Beijing Tongren Hospital 2013-10-31
NCT03815435 The Influence of Blood Pressure Upon the Clarity of Surgical Field in Endonasal Surgery https://ClinicalTrials.gov/show/NCT03815435 Completed University Hospital Ostrava 2020-01-31
NCT03809312 The Use of Prophylactic Antibiotics in Endoscopy Sinus Surgery for Chronic Rhinosinusitis With or Without Polyp https://ClinicalTrials.gov/show/NCT03809312 Recruiting CHU de Quebec-Universite Laval 2020-12-31
NCT03783702 Pain Control Following Sinus Surgery https://ClinicalTrials.gov/show/NCT03783702 Recruiting Stanford University 2019-10-01
NCT03781804 Study Evaluating the Efficacy and Safety of Intranasal Administration of OPN-375 in Subjects With Chronic Sinusitis With or Without the Presence of Nasal Polyps https://ClinicalTrials.gov/show/NCT03781804 Recruiting Optinose US Inc. 2020-12-31
NCT03766568 Single Use Device Endoscopy for the Diagnosis of Acute Bacterial Rhinosinusitis in Primary Care https://ClinicalTrials.gov/show/NCT03766568 Recruiting Basel Institute for Clinical Epidemiology and Biostatistics 2020-05-31
NCT03729258 Efficacy and Safety of Modified Release Cefpodoxime Formulation in the Treatment of Acute Sinusitis. https://ClinicalTrials.gov/show/NCT03729258 Recruiting Neutec Ar-Ge San ve Tic A.Åž 2020-10-01
NCT03705793 Effectiveness of Mometasone Nasal Irrigation for Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT03705793 Completed Washington University School of Medicine 2020-02-15
NCT03704415 Aggravated Airway Inflammation: Research on Genomics and Optimal Operative Treatment (AirGOs Operative) https://ClinicalTrials.gov/show/NCT03704415 Recruiting Helsinki University Central Hospital 2023-12-31
NCT03687515 Efficacy and Safety of Budesonide Inhalation Suspension for the Treatment of Chronic Rhinosinusitis With Polyposis. https://ClinicalTrials.gov/show/NCT03687515 Completed Beijing Tongren Hospital 2016-12-03
NCT03675022 Effect of Dupilumab on Sleep Apnea in Patients With Rhinosinusitis https://ClinicalTrials.gov/show/NCT03675022 Recruiting Brigham and Women’s Hospital 2020-07-31
NCT03673956 Topical Antibiotics in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT03673956 Recruiting Mayo Clinic 2020-12-01
NCT03661346 Esmolol vs. Labetalol in Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT03661346 Completed The University of Texas Medical Branch, Galveston 2018-03-30
NCT03614923 Etokimab in Adult Patients With Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) https://ClinicalTrials.gov/show/NCT03614923 Active, not recruiting AnaptysBio, Inc. 2020-09-30
NCT03584178 The Long-Term Safety of Budesonide for Patients With Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT03584178 Recruiting St. Paul’s Hospital, Canada 2020-12-25
NCT03478930 An Extension Study of Omalizumab in Participants With Chronic Rhinosinusitis With Nasal Polyps https://ClinicalTrials.gov/show/NCT03478930 Completed Hoffmann-La Roche 2020-03-16
NCT03450083 Benralizumab Effect on Severe Chronic Rhinosinusitis With Eosinophilic Polyposis https://ClinicalTrials.gov/show/NCT03450083 Completed Johns Hopkins University 2020-01-01
NCT03439865 Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT03439865 Recruiting University of Alabama at Birmingham 2021-05-31
NCT03431337 Treatment of Acute Sinusitis With High-Dose vs. Standard-Dose Amoxicillin/Clavulanate https://ClinicalTrials.gov/show/NCT03431337 Recruiting Albany Medical College 2021-03-31
NCT01253577 A Clinical Evaluation of a Steroid-Coated Sinus Stent When Used Following Functional Endoscopic Sinus Surgery in Patients With Chronic Sinusitis https://ClinicalTrials.gov/show/NCT01253577 Completed Intersect ENT 2010-10-31
NCT01205984 Systemic Methylprednisolone in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT01205984 Completed Ondokuz Mayıs University 2009-09-30
NCT01198912 Influence of Oral Doxycycline on Wound Healing After Endonasal Endoscopic Sinus Surgery for Chronic Rhinosinusitis With and Without Nasal Polyposis: a Double-blind Randomized Placebo-controlled Trial https://ClinicalTrials.gov/show/NCT01198912 Completed University Hospital, Ghent 2016-09-06
NCT01179139 Pathogenesis of Chronic Sinusitis in Relationship to Tobacco Smoke Exposure https://ClinicalTrials.gov/show/NCT01179139 Completed Massachusetts General Hospital 2010-07-31
NCT01166945 Short (5 Days) Versus Long (14 Days) Duration of Antimicrobial Therapy for Acute Bacterial Sinusitis in Children https://ClinicalTrials.gov/show/NCT01166945 Completed University of Wisconsin, Madison 2016-02-29
NCT01146860 Efficacy and Safety of a Herbal Medicinal Product (Dry Extract BNO 1016) in Patients With Acute Rhinosinusitis https://ClinicalTrials.gov/show/NCT01146860 Completed Bionorica SE 2010-04-30
NCT01197612 Nasal Packing as a Drug Delivery System Postoperatively in Chronic Sinusitis With Polyposis https://ClinicalTrials.gov/show/NCT01197612 Completed University of Michigan 2012-06-30
NCT01118312 Study of Asthma and Nasal Steroids https://ClinicalTrials.gov/show/NCT01118312 Completed JHSPH Center for Clinical Trials 2014-06-30
NCT01115309 XprESS Registry Study https://ClinicalTrials.gov/show/NCT01115309 Completed Entellus Medical, Inc. 2011-12-31
NCT01111669 Intravenous Tranexamic Acid and Intraoperative Visualization During Functional Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT01111669 Completed University of Alberta 2011-12-31
NCT01086839 Sino-nasal Inhalation of Sodium Chloride 6,0% in Patients With Cystic Fibrosis and Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT01086839 Completed University of Jena 2013-04-30
NCT01066104 Subcutaneous Omalizumab for Treatment of Chronic Rhinosinusitis With Nasal Polyposis https://ClinicalTrials.gov/show/NCT01066104 Completed Massachusetts General Hospital 2015-07-31
NCT01050465 MedlinePlus Health Prescriptions: Developing a Pragmatic Approach for Clinic Use https://ClinicalTrials.gov/show/NCT01050465 Completed University of Missouri-Columbia 2010-10-31
NCT01033799 Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers https://ClinicalTrials.gov/show/NCT01033799 Completed Danone Research 2007-04-30
NCT01018030 Dose Finding Study of Fluticasone Furoate Nasal Spray for Uncomplicated Acute Rhinosinusitis https://ClinicalTrials.gov/show/NCT01018030 Completed GlaxoSmithKline 2010-07-01
NCT01007799 Vitamin D for Chronic Sinusitis https://ClinicalTrials.gov/show/NCT01007799 Completed University of Chicago 2011-09-30
NCT00947986 Mucociliary Clearance Time in Chronic Rhinosinusitis (CRS) Patients After Sinus Surgery https://ClinicalTrials.gov/show/NCT00947986 Completed The University of Texas Health Science Center, Houston 2010-02-28
NCT00944515 Efficacy of Azithromycin Prophylaxis in Preventing Recurrent Acute Sinusitis in Children https://ClinicalTrials.gov/show/NCT00944515 Completed Mahidol University 2015-12-31
NCT00939471 Safety and Efficacy of Balloon Sinuplasty in Pediatric Sinusitis https://ClinicalTrials.gov/show/NCT00939471 Completed Acclarent 2009-07-01
NCT00939393 Balloon Sinus Dilation In Office or OR https://ClinicalTrials.gov/show/NCT00939393 Completed Acclarent 2009-06-01
NCT00934830 Antibiotics Versus Therapeutic Ultrasound for Sinusitis https://ClinicalTrials.gov/show/NCT00934830 Completed Norwegian University of Science and Technology 2008-10-31
NCT00924404 Xylitol Versus Saline in Chronic Sinusitis https://ClinicalTrials.gov/show/NCT00924404 Completed University of Iowa 2014-08-31
NCT00912405 Clinical Evaluation of the Steroid-Eluting Sinexus Intranasal Splint When Used Following Functional Endoscopic Sinus Surgery (FESS) in Patients With Chronic Sinusitis https://ClinicalTrials.gov/show/NCT00912405 Completed Intersect ENT 2009-06-30
NCT00871286 Point-of-Care Computed Tomography (CT) Chronic Rhinosinusitis Study https://ClinicalTrials.gov/show/NCT00871286 Completed Northwestern University 2010-08-31
NCT03154541 SynRinse Irrigation Pilot (SIP) Trial https://ClinicalTrials.gov/show/NCT03154541 Completed University of Washington 2018-05-30
NCT01920893 An Evaluation of Dupilumab in Patients With Nasal Polyposis And Chronic Symptoms Of Sinusitis https://ClinicalTrials.gov/show/NCT01920893 Completed Sanofi 2014-11-30
NCT03011632 Response of the Airway in Sinusitis and Asthma https://ClinicalTrials.gov/show/NCT03011632 Completed Medical Universtity of Lodz 2019-08-31
NCT02888730 Tobramycin Delivered by Nebulized Sonic Aerosol for Chronic Rhinosinusitis Treatment of Cystic Fibrosis Patients https://ClinicalTrials.gov/show/NCT02888730 Recruiting Centre Hospitalier Intercommunal Creteil 2022-01-31
NCT02278484 Sinus Balloon Dilation in Pediatric Patients https://ClinicalTrials.gov/show/NCT02278484 Completed Entellus Medical, Inc. 2015-09-30
NCT02217332 Study of Dexpramipexole Chronic Sinusitis With Nasal Polyps and Eosinophilia https://ClinicalTrials.gov/show/NCT02217332 Completed Knopp Biosciences 2016-12-14
NCT02106793 Mitomicin C for Prevention Postoperative Endoscopic Sinus Surgery Synechia and QOL in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT02106793 Completed Mahidol University 2017-12-01
NCT00896883 Evaluation of the Middle Turbinate Implant for Affixing the Middle Turbinate to the Nasal Septum https://ClinicalTrials.gov/show/NCT00896883 Completed ENTrigue Surgical, Inc. 2009-11-30
NCT02266810 Safety and Efficacy of the Propel Mini and Propel Nova Steroid-Eluting Sinus Implant in Frontal Sinus https://ClinicalTrials.gov/show/NCT02266810 Completed Intersect ENT 2016-04-30
NCT00791934 Clinical Study of Safety and Efficacy for the Relieva Stratus With Elution of Triamcinolone Acetonide https://ClinicalTrials.gov/show/NCT00791934 Completed Acclarent 2011-11-30
NCT00751075 Effectiveness and Safety of Once or Twice Daily Mometasone Nasal Spray Versus Amoxicillin Versus Placebo for Treatment of Acute Rhinosinusitis (Phase 3 Study)(Study P02692) https://ClinicalTrials.gov/show/NCT00751075 Completed Merck Sharp & Dohme Corp. 2004-05-06
NCT00750750 Effectiveness and Safety of Once or Twice Daily Mometasone Nasal Spray Versus Amoxicillin Versus Placebo for Treatment of Acute Rhinosinusitis (Study P02683) https://ClinicalTrials.gov/show/NCT00750750 Completed Merck Sharp & Dohme Corp. 2003-09-01
NCT00747747 Sinuclean’s Treatment Of Sinusitis’ Symptoms https://ClinicalTrials.gov/show/NCT00747747 Completed Galsor S.r.l. 2009-01-31
NCT00739921 The Polymerase Chain Reaction (PCR) Analysis of Nasal Polyps for Fungal DNA https://ClinicalTrials.gov/show/NCT00739921 Completed University of California, San Francisco 2015-05-31
NCT00683371 Microarray Analysis of Sinus Samples From Patients With and Without Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT00683371 Completed University of California, San Francisco 2008-04-30
NCT00668304 Trial to Evaluate Time to Symptom Relief and Elimination of Infecting Bacteria in Treating Sinusitis With Avelox https://ClinicalTrials.gov/show/NCT00668304 Completed Bayer NA
NCT00645762 Balloon REmodeling Antrostomy THErapy Study https://ClinicalTrials.gov/show/NCT00645762 Completed Entellus Medical, Inc. 2010-06-30
NCT00645073 Study of the Safety and Efficacy of Cefdinir and Levofloxacin for the Treatment of Subjects With Acute Bacterial Sinusitis https://ClinicalTrials.gov/show/NCT00645073 Completed Abbott 2004-03-31
NCT00644553 Comparative Study of the Safety and Efficacy of Clarithromycin Extended-Release Tablets Versus Amoxicillin-Clavulanate for the Treatment of Acute Bacterial Sinusitis https://ClinicalTrials.gov/show/NCT00644553 Completed Abbott 2004-03-31
NCT00643409 A Multicenter, Randomized, Double-Blind, Double-Dummy Trial of Azithromycin SR Compared With Levofloxacin for the Treatment of Sinus Infections in Adults https://ClinicalTrials.gov/show/NCT00643409 Completed Pfizer NA
NCT00634608 Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow https://ClinicalTrials.gov/show/NCT00634608 Completed University of Missouri-Columbia 2009-03-31
NCT00626366 Distribution of Topical Nasal Medication Within the Nasal Cavity and Sinuses by Radiographic Comparison https://ClinicalTrials.gov/show/NCT00626366 Completed University of Nebraska 2009-01-31
NCT00610779 Treatment of Acute Rhino-Sinusitis With Essential Oils of Aromatic Plants https://ClinicalTrials.gov/show/NCT00610779 Completed HaEmek Medical Center, Israel 2008-05-31
NCT00588016 Concentration of Itraconazole Solution in Nasal Secretions https://ClinicalTrials.gov/show/NCT00588016 Completed Mayo Clinic 2013-12-31
NCT00554190 Study to Evaluate Safety and Effectiveness of AdvaCoat Sinus Gel https://ClinicalTrials.gov/show/NCT00554190 Completed Carbylan Therapeutics, Inc. 2007-12-31
NCT00552773 Pilot Study to Determine Efficacy of Cyclamen Europaeum Extract Nasal Spray in Patients With Acute Sinusitis https://ClinicalTrials.gov/show/NCT00552773 Completed Dey 2008-09-30
NCT00537563 AMS VS MOXI Ketek vs Avelox in AMS https://ClinicalTrials.gov/show/NCT00537563 Completed Sanofi 2003-09-30
NCT00534768 Postoperative Treatment After Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT00534768 Completed Kuopio University Hospital NA
NCT00534079 Nasal Inhalation of Pulmozyme in Patients With Cystic Fibrosis and Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT00534079 Completed University of Jena 2009-02-28
NCT00492024 BAY12-8039: 5 Days for Sinusitis vs Placebo https://ClinicalTrials.gov/show/NCT00492024 Completed Bayer 2008-03-31
NCT00465530 Comparing the Use of Saline or Saline Plus Gentamycin in Nasal Irrigation to Treat Chronic Sinusitis in Children https://ClinicalTrials.gov/show/NCT00465530 Completed University of Kansas Medical Center 2010-03-31
NCT00447837 Evaluating SPRC-AB01 in Post-Surgical Subjects With Chronic Sinusitis https://ClinicalTrials.gov/show/NCT00447837 Completed Naryx Pharma 2007-12-31
NCT00425620 Amphotericin B Suspension in Refractory Chronic Sinusitis https://ClinicalTrials.gov/show/NCT00425620 Completed Accentia Biopharmaceuticals NA
NCT00416182 Nasally Delivered Pulmozyme for Sinusitis in Cystic Fibrosis https://ClinicalTrials.gov/show/NCT00416182 Completed University of Vermont 2012-06-30
NCT00410735 Study of ONO-1078 in Patients With Chronic Sinusitis https://ClinicalTrials.gov/show/NCT00410735 Completed Ono Pharmaceutical Co. Ltd 2008-06-30
NCT00396162 Use of Probiotics as Adjunctive Treatment for Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT00396162 Completed University of Michigan 2008-01-31
NCT00377403 Treatment of Acute Sinusitis https://ClinicalTrials.gov/show/NCT00377403 Completed Washington University School of Medicine 2009-05-31
NCT00368823 A Trial of Point of Care Information in Ambulatory Pediatrics https://ClinicalTrials.gov/show/NCT00368823 Completed University of Washington NA
NCT00367120 Zmax Compared to Augmentin in Sinusitis https://ClinicalTrials.gov/show/NCT00367120 Completed Pfizer NA
NCT00335309 Maxillary Sinus Irrigation in the Management of Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT00335309 Completed Carmel Medical Center 2013-08-31
NCT00265434 Nasal Inhalation of Dornase Alfa (Pulmozyme) in Patients With Cystic Fibrosis and Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT00265434 Completed University of Jena 2006-05-31
NCT00249210 A Study of the Safety and Effectiveness of Levofloxacin Compared With Amoxicillin/Clavulanate Potassium in the Treatment of Adults With Rapid Onset of Severe Inflammation/Infection of the Sinuses https://ClinicalTrials.gov/show/NCT00249210 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. NA
NCT00245427 Outcomes of Patients Not Responding to Antibiotics in the Community https://ClinicalTrials.gov/show/NCT00245427 Completed CPL Associates NA
NCT00242437 Hemostatic Matrix in Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT00242437 Completed Ethicon, Inc. NA
NCT00236652 A Study Evaluating the Safety and Efficacy of Treating Sinus Infection With Levofloxacin 750 mg for 5 Days. https://ClinicalTrials.gov/show/NCT00236652 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. NA
NCT00236522 A Comparison of the Safety and Efficacy of Two Different Regimens of Levofloxacin in the Treatment of Acute Bacterial Sinusitis(Sinus Infection) in Adults. https://ClinicalTrials.gov/show/NCT00236522 Completed Johnson & Johnson Pharmaceutical Research & Development, L.L.C. NA
NCT00232154 A Study To Measure The Level Of Drug In Nasal Tissue And Blood After Taking A Single 2g Dose Or 500mg Tablets For Up To https://ClinicalTrials.gov/show/NCT00232154 Completed Pfizer 2006-06-30
NCT00231062 Clinical Evaluation to Confirm Safety and Efficacy of Sinuplasty in the Paranasal Sinuses (CLEAR) https://ClinicalTrials.gov/show/NCT00231062 Completed Acclarent 2006-06-30
NCT00208065 Evaluation of Histamine, CGRP and VIP as Markers for Activation of Trigeminal and Parasympathetic Nerve Fibers https://ClinicalTrials.gov/show/NCT00208065 Completed Clinvest 2005-11-30
NCT00184392 Cleaning of the Nose After Sinus Surgery: Necessary or Only Bothersome? https://ClinicalTrials.gov/show/NCT00184392 Completed Norwegian University of Science and Technology 2005-12-31
NCT00174694 CHOOSE : Telithromycin, Acute Bacterial Sinusitis https://ClinicalTrials.gov/show/NCT00174694 Completed Sanofi 2005-12-31
NCT00147914 Comparison Study Between Cefdinir & Amoxicilline/Clavulanate in Acute Sinusitis and Assessment of Quality of Life https://ClinicalTrials.gov/show/NCT00147914 Completed University of Chicago 2007-02-28
NCT00132275 Guidelines for Acute Sinusitis https://ClinicalTrials.gov/show/NCT00132275 Completed University of Pittsburgh NA
NCT00117611 Xolair in Patients With Chronic Sinusitis https://ClinicalTrials.gov/show/NCT00117611 Completed University of Chicago 2007-05-31
NCT00002149 Acupuncture and Herbal Treatment of Chronic HIV Sinusitis https://ClinicalTrials.gov/show/NCT00002149 Completed NIH AIDS Clinical Trials Information Service NA
NCT00004638 Immunologic Aspects of the Pathogenesis of Chronic Sinusitis in Children https://ClinicalTrials.gov/show/NCT00004638 Completed National Center for Research Resources (NCRR) NA

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03250429 Nasal and Peripheral Blood Biomarkers of CRS Patients Before and After Surgical Intervention https://ClinicalTrials.gov/show/NCT03250429 Completed University of North Carolina, Chapel Hill 2018-12-10
NCT02720653 Determinants of Olfactory Dysfunction in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT02720653 Enrolling by invitation Oregon Health and Science University 2021-06-30
NCT02712502 Levofloxacin in Bacterial Rhinosinussitis https://ClinicalTrials.gov/show/NCT02712502 Completed Dr. Reddy’s Laboratories Limited 2014-12-31
NCT02038166 Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT02038166 Recruiting University of Alabama at Birmingham 2020-07-31
NCT02548598 Analysis of Inflammation and Microbiome in Patients With Sinusitis and Asthma https://ClinicalTrials.gov/show/NCT02548598 Active, not recruiting University of California, San Francisco 2017-09-30
NCT02297815 Comparative Effectiveness of Antibiotics for Respiratory Infections https://ClinicalTrials.gov/show/NCT02297815 Completed Children’s Hospital of Philadelphia 2016-04-30
NCT02270125 Nanoparticles in Nasal Mucosa https://ClinicalTrials.gov/show/NCT02270125 Completed University Hospital Ostrava 2017-11-30
NCT02221128 PerClot to Control Bleeding in Endoscopic Sinus Surgery https://ClinicalTrials.gov/show/NCT02221128 Completed CryoLife Europa 2014-09-30
NCT01827176 Clinical Characteristic of Recurrent Acute Rhinosinusitis in Children https://ClinicalTrials.gov/show/NCT01827176 Completed Mahidol University 2014-04-30
NCT01685229 Medical Therapy Versus Balloon Sinus Dilation for Patients With Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT01685229 Completed Acclarent 2015-04-01
NCT01684540 Application of Ectoin® Rhinitis Nasal Spray in Patients With Acute Rhinosinusitis https://ClinicalTrials.gov/show/NCT01684540 Completed Bitop AG 2012-08-31
NCT01671098 Sinonasal Gas Exchange Dynamics https://ClinicalTrials.gov/show/NCT01671098 Completed Louisiana State University Health Sciences Center Shreveport 2015-08-31
NCT01553110 An Observational Study to Evaluate The Relationship of Nasal Mucus Properties and Symptoms https://ClinicalTrials.gov/show/NCT01553110 Completed Virginia Commonwealth University 2018-12-31
NCT01513837 Rinitis y Sinusitis según la Gravedad Del Asma https://ClinicalTrials.gov/show/NCT01513837 Completed Fundació Institut de Recerca de l’Hospital de la Santa Creu i Sant Pau 2012-02-29
NCT01492868 Sinusitis in Children and the Nasopharyngeal Microbiome https://ClinicalTrials.gov/show/NCT01492868 Completed University of Wisconsin, Madison 2017-06-30
NCT01430026 Efficacy and Complication of Gentamicin Nasal Irrigation in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT01430026 Completed Mahidol University 2012-01-31
NCT01402349 Chronic Rhinosinusitis in a Danish Population: Evaluation of Causes of Disease, Progress and Treatment https://ClinicalTrials.gov/show/NCT01402349 Completed Odense University Hospital 2011-04-30
NCT01332136 Determinants of Medical and Surgical Treatment Outcomes in Chronic Sinusitis https://ClinicalTrials.gov/show/NCT01332136 Completed Oregon Health and Science University 2016-03-31
NCT04131686 NAC Inhalation in the Treatment Of Symptomatic acuTe rhinosinUSitis https://ClinicalTrials.gov/show/NCT04131686 Recruiting Boryung Pharmaceutical Co., Ltd 2021-05-30
NCT03975842 Chronic Otitis Media With Effusion in Chronic Sinusitis With Polyps https://ClinicalTrials.gov/show/NCT03975842 Completed Fondation Ophtalmologique Adolphe de Rothschild 2012-12-31
NCT03693976 Non-interventional Study With Ectoin Containing and/or Decongesting Nasal Spray in Patients With Rhinosinusitis https://ClinicalTrials.gov/show/NCT03693976 Completed Bitop AG 2019-04-15
NCT03584737 Point-of-Care Immunoassay for Detection of Bacterial Sinusitis https://ClinicalTrials.gov/show/NCT03584737 Active, not recruiting ENTvantage Dx 2020-08-31
NCT03535558 Fluoroquinolone Associated Disability https://ClinicalTrials.gov/show/NCT03535558 Completed Janssen Research & Development, LLC 2018-12-31
NCT03480100 Non-interventional Study of Ectoin Nasal Douche (END01) in Patients With Acute Viral Rhinosinusitis https://ClinicalTrials.gov/show/NCT03480100 Completed Bitop AG 2018-05-31
NCT03466879 A User Study of SYNUS Pain Relief Made by Tivic Health Systems https://ClinicalTrials.gov/show/NCT03466879 Completed Tivic Health Systems 2018-07-21
NCT01255566 Medical Therapy Versus Sinus Surgery for Chronic Rhinosinusitis: A Prospective, Multi-institutional Study https://ClinicalTrials.gov/show/NCT01255566 Completed Oregon Health and Science University 2012-07-31
NCT01156701 Prophylactic Efficacy of Relenza Against Influenza A and B https://ClinicalTrials.gov/show/NCT01156701 Completed GlaxoSmithKline 2010-05-31
NCT01129765 Home Usability of a Nasal Lavage System in Children https://ClinicalTrials.gov/show/NCT01129765 Completed Aardvark Medical Company 2009-08-31
NCT01107379 Optimization and Refinement of Technique in In-Office Sinus Dilation 2 https://ClinicalTrials.gov/show/NCT01107379 Completed Acclarent 2012-01-31
NCT01032174 Non-Interventional Open Label Prospective Comparative Observational Study Of Evaluation Of Compliance In The Empiric Treatment With Azithromycin SR Versus Amoxiclav 1000 Mg In Adult Patients With Of Acute Bacterial Maxillary Sinusitis https://ClinicalTrials.gov/show/NCT01032174 Completed Pfizer 2011-03-31
NCT01002313 Effect of Prednisone onTregs and TH17 https://ClinicalTrials.gov/show/NCT01002313 Completed University of Chicago 2010-05-31
NCT01001819 DNA Microarray Analysis of Gene Expression in Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT01001819 Completed Montefiore Medical Center 2008-11-18
NCT01001039 Validation of the Facial and Cephalic Pain Inventory https://ClinicalTrials.gov/show/NCT01001039 Completed University of Washington 2011-07-31
NCT00970190 Olfactory Dysfunction of Rhinosinusitis - Cyclic Adenosine Monophosphate (cAMP)/Calcium Signaling Study https://ClinicalTrials.gov/show/NCT00970190 Completed University of Washington 2014-04-30
NCT00962689 Clinical Study to Improve Diagnosis and Treatment of Sinusitis https://ClinicalTrials.gov/show/NCT00962689 Completed Ohio State University 2013-11-30
NCT00930488 Treatment of Patients With Acute Sinusitis https://ClinicalTrials.gov/show/NCT00930488 Completed Bayer 2008-12-31
NCT00847041 Microarray Analysis of Sinus Samples From Patients With and Without Chronic Rhinosinusitis. https://ClinicalTrials.gov/show/NCT00847041 Completed University of California, San Francisco NA
NCT00843869 Reversal of Tobacco-Related Sinusitis https://ClinicalTrials.gov/show/NCT00843869 Completed University of Alabama at Birmingham 2015-02-28
NCT04418622 Evolution of the Endonasal Microbiota in Patients With Chronic Rhinosinusitis https://ClinicalTrials.gov/show/NCT04418622 Recruiting University Hospital, Brest 2021-06-02
NCT00543998 Near Infrared Transillumination of the Paranasal Sinuses https://ClinicalTrials.gov/show/NCT00543998 Completed University of California, Irvine 2005-06-30
NCT00517946 A Study To Investigate If MRI Scanning Is Effective At Seeing What Hayfever Drugs Do In Nasal Passage. https://ClinicalTrials.gov/show/NCT00517946 Completed GlaxoSmithKline 2007-04-30
NCT00355160 Non-Rhinologic Etiologies of Headaches and Facial Pain in Tertiary Care Setting https://ClinicalTrials.gov/show/NCT00355160 Completed Penn State University 2009-04-30
NCT00292851 Blown Nasal Secretion Measurements in Rhinosinusitis: Repeatability and Validity Compared to Nasal Lavage https://ClinicalTrials.gov/show/NCT00292851 Completed St. Joseph’s Healthcare Hamilton NA
NCT00799097 Determinants of Surgical Outcomes in Chronic Sinusitis https://ClinicalTrials.gov/show/NCT00799097 Completed Oregon Health and Science University 2009-06-30
NCT00266474 Prevalence of Chronic Rhinosinusitis in Cystic Fibrosis https://ClinicalTrials.gov/show/NCT00266474 Completed University of Jena NA
NCT00797004 Olfactory Dysfunction of Rhinosinusitis https://ClinicalTrials.gov/show/NCT00797004 Completed University of Washington 2010-09-30

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03379701 Applications of Nanotechnology and Chemical Sensors for the Detection and Identification of Chronic Sinusitis Subtypes by Respiratory Samples https://ClinicalTrials.gov/show/NCT03379701 Completed Hillel Yaffe Medical Center 2016-09-27